Carrier screening is a type of genetic test can help you find out if you carry a mutation for certain inherited genetic conditions that could be passed on to your child. Many of us are carriers of several genetic conditions, usually without any symptoms and without affecting our health. However, when two people are carriers for the same genetic condition and have children together, there is a one in four chance for the child inherting two mutated genes from both parents can have the genetic condition. Generally, the conditions detected by carrier screen are quite serious causing death or serious disability in early childhood. Hence, carrier screen helps to decrease this risk.
Examples of genetic conditions range from Deafness to more debilitating conditions such as Sickle Cell Disease (1) which can significantly affect a child's quality of life and reduce life expectancy.
At Circle, we believe in the empowerment of individuals to take control of their health through the knowledge of their genetic blueprint. Using next-generation whole-exome sequencing technology, the Circle Family Planning test analyses DNA samples to identify genetic risk for 155+ inherited genetic conditions. Knowing you and your partner's risk profile before pregnancy allows you to consider your options with time to make choices. Your healthcare provider can guide you on your available options.
(1) Sickle Cell Disease is an inherited blood disorder which affects a major component of red blood cells, hemoglobin, and results in red blood cells having a stiff crescent shape resembling a sickle. Adequate levels of red blood cells and hemoglobin are needed for efficiently delivering oxygen to all the cells in your body. As the sickled blood cells die prematurely, poor delivery of oxygen to our body causes a person to feel weak and tired. These sickled cells can also get stuck in small blood vessels, blocking blood flow and causing serious medical complications such as tissue deterioration.